Our goal is to understand the physiopathology and to discover new treatments for rare disorders involving the PIK3CA/AKT/mTOR pathway.
Our research is supported by the European Commission (European Research Council Starting grant acronym PAPA_Study and European Research Council Proof of Concept grant, acronym CureTheCloves) but also by several Foundations.
The laboratory is located at the Necker Hospital (Paris). The team belongs to the INEM (Institut Necker Enfants Malades) and the Renal division.
The best of scientific research committed to PatientsProfesseur Sébastien Candel
The European Research Council awarded us a Grant for the thrid time! After "PAPAStudy - Podocyte Adaptation Proliferation and Ageing" (Starting Grant - GA n°679254), "CureTheCloves - PIK3CA inhibition in patients with the CLOVES syndrome" (Proof of Concept GA...read more
The name of the lab is changing for this new one: "Mechanisms and therapeutic strategies in overgrowth syndromes and vascular...read more
Congratulations to Quitterie for the prize “Grandes Avancées Françaises en Biologie” from the Académie des Sciences!
On Tuesday, June 25, 2019, the Academy of Sciences invited young researchers / first authors, having contributed to major French scientific advances in biology, to present their results at the Institut de France. The Laureates were awarded with a medal and a prize of...read more