Our goal is to understand the physiopathology and to discover new treatments for rare disorders involving the PIK3CA/AKT/mTOR pathway.
Our research is supported by the European Commission (European Research Council Starting grant acronym PAPA_Study and European Research Council Proof of Concept grant, acronym CureTheCloves) but also by several Foundations.

The laboratory is located at the Necker Hospital (Paris). The team belongs to the INEM (Institut Necker Enfants Malades) and the Renal division.

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The best of scientific research committed to Patients

Professeur Sébastien Candel

President of the French Academy of Sciences


The #COSY project received 10 million euros!

The #COSY project (Cure Overgrowth SYndromes) will support fundamental research, drugs repositioning, creation of an OS department at Necker, development of new imaging modalities, state of the art genetic testing, 1st registry, promote socialization, education and...

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