Our goal is to understand the physiopathology and to discover new treatments for rare disorders involving the PIK3CA/AKT/mTOR pathway.
Our research is supported by the European Commission (European Research Council Starting grant acronym PAPA_Study and European Research Council Proof of Concept grant, acronym CureTheCloves) but also by several Foundations.

The laboratory is located at the Necker Hospital (Paris). The team belongs to the INEM (Institut Necker Enfants Malades) and the Renal division.

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The best of scientific research committed to Patients

Professeur Sébastien Candel

President of the French Academy of Sciences


The team participated to the “TOR de France”

In October 14-15, the team participated to the "TOR de France" conference. Guillaume Canaud delivered a lecture on new developments for PIK3CA-Related overgrowth spectrom and the team presented a poster on the Impact of PIK3CA Gain-of-function mutation in renal and...

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